CALGARY (660 NEWS) – Calgary employees were ordered to walk off the job at 6 p.m. Wednesday night as part of the Canada Post rotating strikes.The Canadian Union of Postal Workers (CUPW) made the announcement over its website earlier in the day to report to their locals along with members from Kelowna and Toronto.The move comes after the federal government had named a special mediator earlier in the day in hopes of ending this job action.“There will be no delivery of mail or parcels or pick-ups,” said Canada Post spokesperson Jon Hamilton. “There will likely be pickets set up at our facilities, the rest of our network will remain open but we’ll wait to see where they shut down but you can count on the mail processing facility, the depot, and the post offices.”Hamilton says service will resume as soon as the workers return to the job after that 24 hour period.“Negotiations continue, we have a good offer on the table with wage increases, benefit improvements, job security and no concessions or rollbacks whatsoever,” he said. “Rotating strikes are having an impact on our customers, we’re trying to do everything we can to minimize them and catch up once they end but it is an inconvenience for our customers and we’re doing our best to reduce that inconvenience.”The union has several things it says it wants to be addressed, including job security through the creation of full-time positions.They also want issues addressed concerning parcel deliveries and health concerns around what it deems as precarious work.“We never know, hopefully, it’ll be over soon,” said Casey Hutsul from the picket line. “It’s dead, maybe it’ll last a couple days we’re hoping.”“We’re trying to get the employer to negotiate,” said Anna Beale, Executive Vice-President of the Calgary local of the Candian Union of Postal Workers. “And they just seem to have, I don’t know if it’s come to a standstill or they want someone else to push them but we’re here to say we want you to negotiate properly and fairly.”Beale says they are in favour of the increased workload they’re seeing with parcel delivery but it has to be done safely.“We’re also looking at making it a better pay equity system … we’re trying to get it so whoever does the same work gets the same pay.”Canada Post has warned customers there could be delays as these walkouts continue.CUPW represents 50,000 employees nationwide.
Islamabad: Pakistan’s seriousness to act against proscribed terror outfits and its efforts to curb money laundering and terror financing were questioned by members of a regional affiliate of the Financial Action Task Force (FATF) at a meeting held in China, according to a media report. A 10-member delegation, led by Finance Secretary Mohammad Younas Dagha, attended the two-day meeting of the Asia-Pacific Group (APG) of the Paris-based FATF in the southern Chinese city of Guangzhou where it defended Pakistan’s efforts against money laundering and terror financing. Also Read – Saudi Crown Prince Salman ‘snubbed’ Pak PM Imran, recalled his private jet from US: ReportAccording to a Dawn report, some participants, particularly those from India, raised very tough questions about Pakistan’s seriousness to act against proscribed organisations and effectiveness of internal controls. On May 3, Finance Minister Arun Jaitley said India will ask the FATF to put Pakistan on a blacklist of countries that fail to meet international standards in stopping financial crime. The APG will submit to the FATF its analysis of the compliance report submitted by Pakistan at the meeting, which concluded yesterday, and the progress made since the group’s on-site inspection in Islamabad and Karachi in March, the report said. Also Read – Iraq military admits ‘excessive force’ used in deadly protestsThe APG report will become the basis for the FATF to decide whether to exclude Pakistan from its grey list or not. The delegation briefed the meeting about Pakistan’s updated actions against currency smuggling, proscribed organisations and tightening of financial and corporate sector systems and operational effectiveness, the report said. Giving examples of the measures taken by it, Pakistan cited arrests of key operatives of some proscribed outfits, putting more such groups and their affiliates in the list of banned outfits, blocking their accounts and financial flows and taking control of their assets. In March, bowing down to international pressure, Pakistan launched a major crackdown on Jaish-e-Mohammad, Jamat-ud-Dawa, Falah-i-Insaniyat Foundation and other banned outfits and took over the control of their assets throughout the country. The Pakistan delegation said the country was very close to accomplish the milestones set under the FATF action plan well before the September deadline. It also said the government recently revised its national risk assessment of the corporate sector, strengthened customs procedures on borders and inland movement of funds and assets. Besides, internal control of the banking and non-banking financial institutions, insurance companies and stock exchanges has been strengthened to curb the possibility of money laundering and terror financing. The delegation cited the creation of a specialised directorate of Cross-Border Currency Movement (CBCM) in Islamabad to maintain a database of currency seizures. The APG had earlier flashed contradictory situations and poor coordination among stakeholders, including law enforcement agencies, in fighting money laundering and terror financing in Pakistan. Last month, it expressed serious reservations over insufficient physical actions on ground against proscribed organisa tions to block flow of funds and activities.
U.S. songstress Mariah Carey was reportedly paid around $1.5 million to perform at a private celebration in London for the son of the Sultan of Brunei on New Year’s Eve, Britain’s Daily Mail reported on Friday.Invited to appear by Prince Azim, Carey is believed to have performed three songs, including Always Be My Baby, and lead a chorus of traditional New Year’s hit Auld Lang Syne.“Prince Azim is known for his lavish star-studded parties, and his 30th birthday in 2012 was attended by the likes of Elizabeth Jagger, Raquel Welch and Pamela Anderson,” the newspaper reported, adding that the party hosting Carey took place at the five-star Dorchester Hotel. Carey and the billionaire prince are believed to have been “friends for a number of years,” the newspaper stated.“Mariah has known Prince Azim for many years … They are friends and have done a lot of charity work together,” a representative for Carey told the newspaper, although they would not discuss how much Carey was paid.The pop diva performed alongside veteran star Diana Ross at the event, which hosted high profile guests including actresses Sophia Loren and Faye Dunaway.But Carey’s New Year’s performance came after she stirred controversy when she was paid an estimated $1m to perform for Angolan President Josè Eduardo Dos Santos last week.The performance prompted human rights campaigners to express their outrage at the news, claiming the leader had murdered and exploited the African country’s people for his own gain.But Carey is not the only pop star to recently come under fire for controversial performances.In July 2013, Jennifer Lopez apologized for singing “Happy Birthday to You” to the president of Turkmenistan.The Human Rights Foundation (HRF) had criticized the performance in a strongly worded statement, prompting the apology. According to the nonprofit, Turkmen President Gurbanguly Berdymukhamedov has “ruled the country with an iron fist since 2006.”Source: Al Arabiya
Under a rare clear London sky, Allyson Felix shot around the track in the 200-meter race like a woman determined to not have a third failure in the event of her life.With 40 meters remaining to cover before the finish line – and the elusive Olympic gold medal – Felix burst pass Shelly-Ann Fraser-Pryce to glory.The disheartening results of previous Olympics mattered not. The gold was hers, and she left no doubt about it, either, winning by .21 seconds.Felix won the race in 21.88 seconds, topping Fraser-Pryce of Jamaica, who won the 100 four nights earlier and Team USA’s Carmelita Jeter, who added a bronze to go with her silver in the 100 meters.One more spot back was Jamaica’s Veronica Campbell-Brown, who defeated Felix in the Athens and Beijing Games and was trying to become the first woman to win the same individual track and field event in three consecutive Olympics.It was the third-place tie in 100-meter qualifying at U.S. trials last month that hovered over Felix’s run-up to these Olympics — forcing her to defend herself off the track for the first time in an otherwise-pristine career.Her tie with Jeneba Tarmoh for the third and final spot in the 100 forced USA Track and Field officials to scramble for a solution. One possibility was a coin flip; instead, they settled on a run-off. But Tarmoh begged off. Felix, never a serious medal contender for the 100, had to defend her decision not to give up the spot, and she went on to finish fifth.“Everyone just expected me to give up this spot, because I think lots of people … know me and they know that I’m seen as this very nice girl,” Felix said with a chuckle a few days before the start of track and field in London. “But it’s not just about me.”On this night, finally, it was.
Sophomore Kyle Skinner gets ready to serve the ball on at the game on Jan. 18 at St. John Arena in Columbus. Credit: Ethan Clewell | Senior Lantern ReporterFollowing a trip to the West Coast, the Ohio State men’s volleyball team will try and earn a win after losing three straight when the Buckeyes travel to Missouri to take on Lindenwood Friday, and Quincy on the road in Illinois Saturday. The Buckeyes (4-8, 0-2) are looking for their first win since their four-set victory against Lincoln Memorial at home on Feb. 2. They’ve lost nine straight sets since then to then-unranked Purdue Fort Wayne, No. 6 UC Santa Barbara and No. 1 Long Beach State. Ohio State is also going for its first league win after losses to the Mastodons and then-No. 13 Ball State earlier this season.Head coach Pete Hanson said he’s trying to get his young team to find ways to keep momentum when the match is on the line. “We’re still just making some young errors at really critical times that can keep momentum going,” Hanson said. “A lot of times, that’s what this game is all about: Can you keep a scoring run going or can you stop a scoring run by the other team? We’re just struggling to kind of find ways to get those two things accomplished and a lot of that is youth right now.” Both the Lions and the Hawks share identical records with the Buckeyes. Lindenwood (4-8, 0-2) comes into the match on Friday fresh off losses to No. 10 Lewis and then-No. 8 Loyola Chicago. The Lions are led by redshirt sophomore Charley Hlavin, who has accounted for 103 kills, 52 digs and six aces this season. The Lions and the Buckeyes have had two common opponents this season: Penn State and Saint Francis. Both teams are 1-1, with the Buckeyes having beaten Penn State at home, while the Lions have a five-set road win against the the Red Flash. Quincy (4-8, 0-2) will face the Buckeyes Saturday after having played against league foe McKendree two nights before. The Hawks are currently on their own three-match losing streak, featuring straight-set defeats against then-No. 8 Loyola Chicago and No. 10 Lewis and a four-set loss to Lourdes. The Hawks are led by junior outside hitter Omari Wheeler, who has amassed 160 kills, 60 digs and eight aces this season. Both the Buckeyes and the Hawks fell in straight-sets to their only common opponent: No. 1 Long Beach State. Ohio State will have to lean on the youth on its roster to come up big this weekend. Injuries to major contributors such as senior setter Sanil Thomas and sophomore opposite hitter Jake Hanes have given some younger players more opportunities. Freshman outside hitter Jack Stevens, a serving specialist for the Buckeyes, said he’s been learning a lot from the upperclassmen about how to adjust to playing at the collegiate level. “All the older guys have taught me a lot about just the hard work and dedication it takes to succeed at this level, whether it’s in the practice gym, the weight room, or in the classroom,” Stevens said. “All these guys have been working hard for four or five years. It’s really cool to learn from them.” Ohio State will face Lindenwood at 8 p.m. Friday in Saint Charles, Missouri, and Quincy at 8 p.m. Saturday in Quincy, Illinois.
Fulham Football Club player Andre Schurrle has revealed that scoring his first goal for the club is an amazing moment.The former Chelsea winger was on target for the Cottagers this weekend, scoring the club’s fourth goal during their impressive victory over Burnley on Sunday afternoon.Schurrle is currently on a two-year loan deal from Borussia Dortmund and the Germany international is keen to rekindle his career after a very difficult 24-month spell in the Bundesliga.A beaming Schürrle shared his delight with FulhamFCTV, as quoted by HammyEnd, after the final whistle: “It was a great atmosphere and it was a really good feeling on the pitch. I really enjoyed every minute because you could feel like everyone was coming, everyone was going – the crowd wanted us to be together, fight and score the goals and that’s what we did.”“Today was amazing and for our new players it was so important, you can’t even believe.”Official: Tottenham sign Fulham youngster Ryan Sessegnon Andrew Smyth – August 8, 2019 Tottenham have sealed another transfer deadline day deal to sign the highly-rated Ryan Sessegnon from Fulham.“We could have scored more, especially me. I think I had 45 shots today! Normally in a Premier League you don’t have so many shots and so many big chances, so that’s what we have to get together.”“Maybe we have to score a few more goals, but we’re happy with four today and the win.”The winger was delighted to get off the mark for the Whites, especially after seeing a number of his earlier efforts well saved by Joe Hart.“When I scored the goal, it was very important for me. It was one of the greatest moments in my career and to be on this pitch and in front of these fans, because they were all chanting [my name] before, I wanted to give them something back and when the ball went in and I could feel this joy, it was an amazing moment.”
Antonio Valencia may likely leave Manchester United at the end of the season and is already negotiating with Inter Milan, according to reports in Italy.The approach towards the 33-year-old right-back had already been mentioned in Italy.Reports from Football Italia claims that talks over personal terms have already begun.Valencia will be a free agent when his contract at Old Trafford expires in June and he intends to walk away after 10 years at the club.Lukaku backed to beat Ronaldo in Serie A scoring charts Andrew Smyth – September 14, 2019 Former Inter Milan star Andy van der Meyde is confident Romelu Lukaku will outscore Cristiano Ronaldo in this season’s Serie A.The Ecuador international joined the Red Devils from Wigan in 2009 as a winger, but has transformed into an effective right-back.Although Manchester United do have an option to extend the contract by 12 months, it does not look as if they’re going to use it.Inter Milan are currently fighting for a place in the Champions League in the Serie A and may still qualify via the Europa League if they get their hands on the trophy.
Related Items: Facebook Twitter Google+LinkedInPinterestWhatsAppResponding to the ‘A’ grades his government was given for too much ‘Travelling’ by the Opposition PDM in their recent report card of the government’s first year in office, Premier Hon Rufus Ewing, finally gave reaction. The Premier said that the opposition can say anything, while explaining that as a government and even as a person sometimes you have to branch out and make contact. The country’s leader believes travel is important to networking and building the country. Facebook Twitter Google+LinkedInPinterestWhatsApp
A little more than a week after announcing it was eliminating 111 employees and consolidating positions company-wide, Emmaus, Pennsylvania-based Rodale Tuesday reported third quarter revenue was down 5 percent compared to the same period last year. Meanwhile, revenue through the first nine months was up 2.5 percent.As a privately held company, Rodale did not release specific figures but attributed its year-to-date revenue growth to continued expansion of its Women’s Health and Best Life magazine brands and to revenue from the Flat Belly Diet! and Eat This, Not That! books. Rodale expects to sell more than one million copies of each book by year’s end.“While our advertising is affected by the market downturn, we’ve been able to achieve our profit goals by delivering books, magazines and online products digitally to our growing global audience,” president and CEO Steven Murphy said in a statement. Rodale, it says, saw third quarter digital revenue—including from its magazine sites—increase 22.7 percent over the same period in 2007. Online advertising for its magazine sites was up 18 percent while print advertising revenue was down 1.7 percent.Revenue for the Men’s Health brand—including sales from Eat This, Not That!—increased 10.7 percent during the third quarter, the company said. Advertising revenue at magazine, which saw ad pages fall 14.8 percent during the quarter, decreased 11 percent. Online revenue was up 30 percent.The Women’s Health brand recorded the largest growth with combined revenue increasing 38 percent over the third quarter in 2007. Also seeing growth during the quarter was the Best Life brand (30.4 percent), the Runner’s World Media Group—which includes Runner’s World and Runner’s Times magazines (10 percent) and Organic Gardening (25.7 percent).Revenues were down at Rodale’s Cycling Group—which includes Bicycling and Mountain Bike magazines (-22.8 percent), Rodale Books (-15 percent) and its direct marketing group (-17 percent).Rodale said the layoffs and staffing consolidations were necessary “in order to shift resources toward its highest growth potential activities,” including its online, book and international businesses. Rodale has launched 11 international magazine editions so far this year.
WILMINGTON, MA — Below is advice from the Wilmington Board of Health published in the most recently Town Topics newsletter:Mosquito and tick season is upon us, the Board of Health would like to remind residents to take precautions to reduce their risk of exposure to mosquitoes and ticks.MOSQUITOES – Try to avoid outdoor activity during times of day with increased mosquito activity, which is dawn and dusk. Use mosquito repellents containing an EPA-approved active ingredient such as DEET.Residents should wear long sleeved clothing to reduce mosquito access to skin and remove any standing water in your yard, including children’s toys, birdbaths, pots and planters.Wilmington is part of the Central Massachusetts Mosquito Control Project and routine spraying and larvicide treatment is conducted throughout the summer.TICKS – Ticks are prevalent in Wilmington. Ticks like damp, shady, brushy, leafy areas. If you have been in an area where ticks might be present, it is important to check yourself, your family and your pets for ticks every day. Use repellents that contain DEET on your exposed skin and those that contain permethrin on your clothes. When spending time outside, if weather permits, wear long-sleeved, light colored shirts and long pants tucked into your socks.Keep the grass cut short and remove piles of leaves and brush. Talk to your veterinarian about the best ways to protect your pets and livestock from ticks.If you find a tick on yourself, remove it carefully as soon as possible. If you develop a rash or other signs of illness following a tick bite, be sure to contact your health care provider immediately. If you are looking into preventative tick control, check out tick tubes, which may be found online. They work great ridding areas of deer ticks only. Remember deer ticks are the ones that transmit Lyme Disease. If you have been bitten by a tick, log on to the Board of Health website for links to get the ticks tested.Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email firstname.lastname@example.org.Share this:TwitterFacebookLike this:Like Loading… RelatedWilmington Board Of Health Offers Advice On Mosquitoes & TicketsIn “Government”Wilmington Board Of Health Urges Residents To Use Caution As Mosquitos Test Positive For EEE In AndoverIn “Government”Request A Free Mosquito Spraying From Central Mass. Mosquito Control Project This SeptemberIn “Government”
Share this:TwitterFacebookLike this:Like Loading… RelatedMIDDLESEX DA: Billerica Man Indicted For Alleged Child Rape In WilmingtonIn “Police Log”Middlesex DA: Medford Man Indicted For Wilmington RapeIn “Police Log”Middlesex DA: Wilmington Man Indicted For Attempted MurderIn “Government” WOBURN, MA — Below is an announcement from the Middlesex District Attorney’s Office:The below indictments were handed down between May 2 and June 27, 2019. Defendants are listed by towns where alleged offenses occurred. Defendants without a hometown listed do not have a last known address. These charges are allegations and the defendants are presumed innocent until proven guilty.ArlingtonAngel Rodriguez, 24, of Lynn, was charged with trafficking fentanyl, distribution of a Class A substance, and distribution of a Class B substance. The Assistant District Attorney is Andrew Ineson.AyerJohn Thompson, 29, of Ayer, was charged with home invasion and masked armed robbery. The Assistant District Attorney is Whitney Williams.BelmontEric Ray, 49, of Belmont, was charged with rape. The Assistant District Attorney is Ceara Mahoney.BillericaJack Albertian, 64, of Georgetown, was charged with rape of a child (2 counts). The Assistant District Attorney is Marisa Tagliareni.Edward Flynn, 56, was charged with breaking and entering in the daytime to commit a felony and larceny in a building. The Assistant District Attorney is Daniel Harren.BoxboroughMichael Riley, 41, of Acton, was charged with larceny over $1,200 and fraudulent use of a credit card over $1,200. The Assistant District Attorney is Raquel Frisardi.CambridgeDante Conner, 21, of Boston, was charged with possession of a firearm during the commission of a felony (2 counts), possession of a large capacity firearm, possession of a large capacity feeding device, possession of a firearm without a license (2 counts), possession of ammunition (3 counts), possession with intent to distribute a Class B substance (2 counts), possession with intent to distribute a Class D substance, and solicitation of tampering with evidence in an official proceeding. The Assistant District Attorney is Maren Schrader.Cassandra Cordeiro, 17, of Cambridge, was charged with assault and battery with a dangerous weapon, masked armed robbery, and being a youthful offender (2 counts). The Assistant District Attorney is Terence Kiernan.Patrick Cowart, 22, was charged with aggravated rape of a child (2 counts). The Assistant District Attorney is Courtney Linnehan.Carolina Elawad, 16, of Cambridge, was charged with assault and battery with a dangerous weapon, masked armed robbery, and being a youthful offender (2 counts). The Assistant District Attorney is Terence Kiernan.Matthew Haley, 27, of Middleton, was charged with possession of a large capacity firearm, possession of a large capacity magazine, possession of a firearm without a license (2 counts), possession of ammunition (2 counts), and being an armed career criminal (4 counts). The Assistant District Attorney is Maren Schrader.Katherine Hawes, 53, of Cambridge, was charged with larceny from a person over the age of 65, larceny from a person, and receiving a stolen credit card. The Assistant District Attorney is Terence Kiernan.Franchesca Polanco-Rivera, 17, Cambridge, was charged with assault and battery with a dangerous weapon, masked armed robbery, and being a youthful offender (2 counts). The Assistant District Attorney is Terence Kiernan.John Kargul, 57, of Brockton, was charged with larceny over $250 by a single scheme (3 counts), credit card fraud over $250 (17 counts), identity fraud by obtaining personal information of another without authorization (12 counts), identity fraud by posing as another (19 counts), money laundering, and being a common and notorious thief. The Assistant District Attorney is Doug Cannon.William Pires, 19, of Somerville, was charged with armed assault with intent to murder, attempted assault and battery with a dangerous weapon by discharging a firearm, possession of a firearm without a license, carrying a loaded firearm, discharging a firearm within 500 feet of a dwelling, and assault with a dangerous weapon. The Assistant District Attorney is Terence Kiernan.Standly Miranda, 27, of Cambridge, was charged with possession of a firearm during the commission of a felony (2 counts), possession of a large capacity firearm, possession of a large capacity feeding device, possession of a firearm without a license (2 counts), possession of ammunition (3 counts), possession with intent to distribute a Class B substance (2 counts), possession with intent to distribute a Class D substance, and solicitation of tampering with evidence in an official proceeding. The Assistant District Attorney is Maren Schrader.Sidney Pierre, 32, was charged with trafficking over 18 grams of cocaine, possession with intent to distribute methamphetamine, subsequent offense, conspiracy to violate the drug laws, and trafficking fentanyl. The Assistant District Attorney is Robert Royce.Franchesca Polanco-Rivera, 16, of Cambridge, was charged with assault and battery with a dangerous weapon, masked armed robbery, and being a youthful offender (2 counts). The Assistant District Attorney is Terence Kiernan.Makalla Pollard, 23, of Boston, was charged with trafficking over 18 grams of cocaine, possession with intent to distribute methamphetamine, conspiracy to violate the drug laws, and trafficking fentanyl. The Assistant District Attorney is Robert Royce.Lesley Rice, 62, of Manchester-by-the-Sea, was charged with larceny over $1,200 by a single scheme (4 counts) and false entry into corporate books (2 counts). The Assistant District Attorney is William R. Freeman.Steca Thelemaque, 28, of Medford, was charged with possession of a firearm without a license, possession of ammunition, possession of a loaded firearm, possession of a Class B substance, and being an armed career criminal (2 counts). The Assistant District Attorney is Maren Schrader.ChelmsfordDaniel Maina, 41, of Tyngsborough, was charged with assault and battery on a person with an intellectual disability and caretaker neglect. The Assistant District Attorney is Heidi Gosule.Isaiah Musoke, 63, of Leominster, was charged with assault and battery on a person with an intellectual disability and caretaker neglect. The Assistant District Attorney is Heidi Gosule.Jennifer Nganga, 60, of Lowell, was charged with assault and battery on a person with an intellectual disability and caretaker neglect. The Assistant District Attorney is Heidi Gosule.ConcordRocco Pelopida, 42, of East Greenwich, Rhode Island, was charged with aggravated rape of a child (3 counts) and child enticement. The Assistant District Attorney is Rachel Perlman.FraminghamWalter Estrada, 33, of Worcester, was charged with trafficking over 100 grams of cocaine. The Assistant District Attorney is Graham Van Epps.Antonis Mallios, 44, of Milford, was charged with felony larceny (10 counts) making false entries into corporate books (2 counts), and being a common and notorious thief. The Assistant District Attorney is Doug Cannon.Emmanuel Osamwonyi, 32, of Framingham, was charged with distribution of cocaine, subsequent offense and as a habitual criminal, possession with intent to distribute cocaine, subsequent offense and as a habitual criminal, and possession with intent to distribute a Class D substance, subsequent offense. The Assistant District Attorney is Robert Meltzer.HudsonDavid Cruz-Gonzales, 33, of Marlborough, was charged with home invasion, kidnapping, stealing by confining or putting a person in fear, assault and battery with a dangerous weapon (2 counts), assault with a dangerous weapon, larceny over $1,200, and possession of burglarious tools. The Assistant District Attorney is Raquel Frisardi.Gary Pimentel, 23, of Worcester, was charged with home invasion, kidnapping, stealing by confining or putting a person in fear, assault and battery with a dangerous weapon (2 counts), assault with a dangerous weapon, larceny over $1,200, and possession of burglarious tools. The Assistant District Attorney is Raquel Frisardi.Carlos Velez, 35, of Marlborough, was charged with home invasion, kidnapping, stealing by confining or putting a person in fear, assault and battery with a dangerous weapon (2 counts), assault with a dangerous weapon, larceny over $1,200, and possession of burglarious tools. The Assistant District Attorney is Raquel Frisardi.Lowell David Aguilar, 58, of Lowell, was charged with armed robbery, assault with a dangerous weapon, and being a habitual criminal. The Assistant District Attorney is Daniel Harren.Matthew Basile, 48, of Stoneham, was charged with trafficking fentanyl, distribution of a Class A substance, subsequent offense, and possession with intent to distribute a Class A substance, subsequent offense. The Assistant District Attorney is Whitney Williams.Jonathan Bennett, 21, was charged with kidnapping, strangulation, assault and battery, breaking and entering in the nighttime to commit a misdemeanor, and threatening to commit a crime. The Assistant District Attorney is Daniel Harren.Jayson Colon, 23, of Lowell, was charged with assault and battery with a dangerous weapon causing serious bodily injury, assault on a household or family member (2 counts), and strangulation. The Assistant District Attorney is Megan McGovern.Korey David, 19, of Lowell, was charged with forcible rape of a child (2 counts), rape of a child (3 counts), indecent assault and battery on a child under the age of 14 (5 counts), and indecent assault and battery on a person over the age of 14 (2 counts). The Assistant District Attorney is Rachel Perlman.Kevin Davidson, 34, was charged with distribution of fentanyl (2 counts), subsequent offense, negligent operation of a motor vehicle, and failure to stop for police. The Assistant District Attorney is Whitney Williams.Jonathan Gacek, 28, of Billerica, was charged with trafficking fentanyl. The Assistant District Attorney is Ashlee Mastrangelo.Kevin Garneau, 49, of Pelham, New Hampshire, was charged with rape (2 counts). The Assistant District Attorney is Thomas Brant.Gina Gentile, 32, was charged with home invasion. The Assistant District Attorney is Clarence Brown.Oliver Godfrey, 20, of Lowell, was charged with larceny from a person (2 counts). The Assistant District Attorney is Whitney Williams.Marcello Lomagno, 32, of Tewksbury, was charged with aggravated rape, kidnapping, assault with a dangerous weapon, indecent assault and battery, and witness intimidation. The Assistant District Attorney is Megan McGovern.Esmeraldo Mena, 25, of Lowell, was charged with trafficking fentanyl and possession with intent to distribute fentanyl. The Assistant District Attorney is Whitney Williams.Jose Mercado, 25, of Lowell, was charged with stalking, witness intimidation (13 counts), assault and battery on a household or family member (5 counts), malicious destruction of property over $1,200, malicious destruction of property under $1,200, malicious destruction of a motor vehicle, assault and battery, violating a restraining order (2 counts), and solicitation, counsel, advise, or enticement of a crime (2 counts). The Assistant District Attorney is Megan McGovern.Chanda Moon, 36, of Lowell, was charged with burglary (2 counts) and larceny from a building (2 counts). The Assistant District Attorney is Whitney Williams.Zachary Noonan, 27, of Lowell, was charged with assault and battery on a household or family member, assault and battery, witness intimidation (4 counts), resisting arrest, kidnapping, and violating a restraining order. The Assistant District Attorney is Megan McGovern.Ezekiel Ramos, 25, of Lowell, was charged with tampering with evidence and solicitation of a felony. The Assistant District Attorney is Suzanne Wiseman.Carlos Rodriguez, 30, of Lowell, was charged with trafficking a Class A substance, trafficking a Class B substance, possession of a firearm without a license, possession of ammunition, possession of a firearm in the commission of a felony, and being an armed career criminal. The Assistant District Attorney is Megan McGovern.Luis Rosario, 28, of Lowell, was charged with trafficking fentanyl. The Assistant District Attorney is Whitney Williams.Zachary Teneriello, 20, of Malden, was charged with witness intimidation. The Assistant District Attorney is Megan McGovern.Randy Velez, 28, was charged with stalking in violation of a restraining order, assault and battery in violation of a restraining order, witness intimidation (2 counts), malicious destruction of property, and violating a restraining order (4 counts). The Assistant District Attorney is Megan McGovern.Rafael Vera, 38, of Lowell, was charged with trafficking fentanyl, use of a firearm in the commission of a felony, possession with intent to distribute a Class B substance, possession with intent to distribute a Class C substance, possession with intent to distribute a Class E substance, possession of a firearm without a license, possession of ammunition, and assault and battery on a household or family member. The Assistant District Attorney is Whitney Williams.Akwasi Yeboah, 24, of Lowell, was charged with home invasion, tampering with evidence, and malicious destruction to a motor vehicle. The Assistant District Attorney is Whitney Williams.MaldenZaina Abdalla, 18, of Malden, was charged with being an accessory after the fact. The Assistant District Attorney is Lee Hettinger.Laurent Beaubrun, 19, of Everett, was charged with possession of a loaded firearm without a license, possession of ammunition, possession of a large capacity feeding device, possession of a firearm with a defaced serial number, possession with intent to distribute a Class C substance, possession with intent to distribute a Class D substance, possession with intent to distribute a Class E substance, and conspiracy to violate the drug laws. The Assistant District Attorney is Michael Klunder.Renan DaSilva, 33, of Saugus, was charged with felony motor vehicle homicide and operating a motor vehicle under the influence of alcohol causing serious bodily injury. The Assistant District Attorney is Lee Hettinger.Josue Espada, 20, of Malden, was charged with being an accessory after the fact and conspiracy to violate the Controlled Substance Act. The Assistant District Attorney is Lee Hettinger.Olivia Filipowich, 18, of Malden, was charged with being an accessory after the fact. The Assistant District Attorney is Lee Hettinger.Marcus Jones, 27, of Randolph, was charged with possession of a firearm without a license (2 counts), subsequent offense, and larceny of a firearm. The Assistant District Attorney is Lee Hettinger.Yahia Mastouri, 18, of Malden, was charged with murder, carrying a firearm without a license, carrying a loaded firearm, assault and battery with a dangerous weapon, and conspiracy to violate the Controlled Substance Act. The Assistant District Attorney is Lee Hettinger.Donnidjy Michel, 20, of Cambridge, was charged with possession of a loaded firearm without a license, possession of ammunition, possession of a large capacity feeding device, possession of a firearm with a defaced serial number, possession with intent to distribute a Class C substance, possession with intent to distribute a Class D substance, possession with intent to distribute a Class E substance, and conspiracy to violate the drug laws. The Assistant District Attorney is Michael Klunder.Eric Pittsley, 41, of Malden, was charged with armed robbery, assault and battery with a dangerous weapon causing serious bodily injury, assault with a dangerous weapon, assault and battery on a household or family member, threatening to commit a crime, and malicious destruction of a motor vehicle. The Assistant District Attorney is Gabrielle Lomanno.MarlboroughWilson Guitierrez, 26, of Framingham, was charged with rape, witness intimidation, assault and battery on a household or family member, and assault with a dangerous weapon (3 counts). The Assistant District Attorney is Courtney Linnehan.Stephen Young, 48, of Marlborough, was charged with failure to register as a sex offender, subsequent offense. The Assistant District Attorney is Robert Meltzer.MedfordMichael Pontonio, 50, of Medford, was charged with trafficking fentanyl and possession with intent to distribute a Class A substance, subsequent offense. The Assistant District Attorney is Robert Meltzer.NatickDavid Missle, 50, of Southborough, was charged with larceny over $250. The Assistant District Attorney is Doug Cannon.Randy Paris, 43, of Mansfield, was charged with indecent assault and battery on a child under the age of 14, posing a child in a state of sexual conduct, and possession of child pornography. The Assistant District Attorney is Rachel Perlman.NewtonPrimo Leung, 36, of Concord, New Hampshire, was charged with aggravated rape of a child (2 counts), indecent assault and battery on a child under the age of 14 by a mandated reporter (2 counts), and indecent assault and battery on a person over the age of 14 (2 counts). The Assistant District Attorney is Radu Brestyan.Jenness Peterson, 23, of Hooket, New Hampshire, was charged with rape (2 counts), assault and battery on a household or family member, strangulation, and trespassing. The Assistant District Attorney is Maren Schrader.ReadingDennis Mercer, 48, of Reading, was charged with aggravated rape of a child (2 counts) and forcible rape of a child (2 counts). The Assistant District Attorney is Courtney Linnehan.SomervilleNeil Alves, 26, of Somerville, was charged with rape and indecent assault and battery on a person over the age of 14. The Assistant District Attorney is Ceara Mahoney.Edward Clark, 55, of Norwood, was charged with leaving the scene of leaving the scene of an accident causing death, leaving the scene of a personal injury, and motor vehicle homicide. The Assistant District Attorney is Terence Kiernan.Rahkeen Gray, 45, was charged with unarmed robbery and armed assault with intent to rob (2 counts). The Assistant District Attorney is Maren Schrader.Sean Romano, 34, of Somerville, was charged with possession of a firearm without a license, possession of ammunition, and possession of a large capacity feeding device. The Assistant District Attorney is Gabrielle Lomanno.TewksburyWesley Fanfan, 23, of Medford, was charged with trafficking fentanyl and conspiracy to violate the drug laws. The Assistant District Attorney is Andrew Ineson.John Doe AKA Luis Hernandez, 36, of Lawrence, was charged with armed assault with intent to murder, assault and battery with a dangerous weapon causing serious bodily injury, kidnapping, witness intimidation, assault and battery on a household or family member (2 counts), subsequent offense, and furnishing a false name to police. The Assistant District Attorney is Emily Jackson.Samil Munoz, 27, of Lawrence, was charged with trafficking over 18 grams of cocaine. The Assistant District Attorney is Ashlee Mastrangelo.Kerby Ulysse, 22, of Cambridge, was charged with trafficking fentanyl and conspiracy to violate the drug laws. The Assistant District Attorney is Andrew Ineson.TownsendJohn Zagwyn, 61, of Shirley, was charged with rape. The Assistant District Attorney is Emily Jackson.TyngsboroughMartin Rojas, 36, of Lawrence, was charged with possession with intent to distribute a Class B substance (2 counts), subsequent offense, and possession with intent to distribute a Class E substance. The Assistant District Attorney is Ashlee Mastrangelo.WalthamStephan Cutone, 50, of Arlington, was charged with breaking and entering in the nighttime to commit a felony (2 counts), breaking and entering in the daytime to commit a felony, larceny from a building (2 counts), possession of a Class B substance, possession of burglarious tools, credit card fraud over $1,200, credit card under $1,200, and malicious destruction of property under $1,200. The Assistant District Attorney is Robert Royce.Samuel Monroy, 32, of Waltham, was charged with assault with intent to rape a child and indecent assault and battery on a child under the age of 14 (3 counts). The Assistant District Attorney is Radu Brestyan.Sigfredo Pena, 38, of Boston, was charged with trafficking fentanyl and possession with intent to distribute cocaine, subsequent offense. The Assistant District Attorney is Robert Royce.Joseph Pierce, 37, of Brockton, was charged with unarmed robbery and assault and battery. The Assistant District Attorney is Robert Royce.WatertownCarlos Guardado, 25, of Watertown, was charged with possession of a firearm without a license, possession of a loaded firearm, possession of ammunition, and possession of a large capacity feeding device (2 counts). The Assistant District Attorney is Robert Royce.Philip Horner, 37, was charged with armed assault with intent to murder, assault and battery with a dangerous weapon causing serious bodily injury, and resisting arrest. The Assistant District Attorney is Joe Gentile.WestonSusan Clark, 62, of Natick, was charged with attempted murder and caretaker abuse and neglect. The Assistant District Attorney is Heidi Gosule.WoburnMichael Nelson, 51, of Woburn, was charged with trafficking of a person for sexual servitude, deriving support from prostitution, and being a habitual criminal. The Assistant District Attorney is Julie Kunkel.Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email email@example.com.
Tags Porsche Taycan on ice in Sweden Porsche Volkswagen Now playing: Watch this: Post a comment Share your voice Enlarge ImageWe’ve already taken the Taycan drifting on ice in Sweden. Now, we just can’t wait to see the darn thing without camouflage. Porsche While the Porsche Taycan electric sports car and the Volkswagen ID 3 electric mass-market hatchback have about as much in common as a tuna fish sandwich and Euler’s formula, they are still both electric cars that happen to offer reservations ahead of production. You might think the much more affordable car would garner a bit more attention than the expensive one; you might also be wrong.According to a report from German-language business newspaper Handelsblatt this weekend, Porsche board member Andreas Haffner indicated that Porsche has 30,000 orders for the Taycan already. This is a pretty large leap from the last estimate we heard in March, when Porsche said over 20,000 people had registered their interest.Consultant and analyst Matthias Schmidt pointed out in a tweet that, according to the most recent data, Porsche has more Taycan reservations than Volkswagen has reservations for the ID 3 electric hatchback. VW’s most recent deposit estimate, about 22,000, came from Jürgen Stackmann, the VW board member responsible for sales and marketing.While it might seem odd that a car with, in all likelihood, at least twice the base price will command more reservations, it makes sense. VW’s ID 3 hatchback is a mass-market vehicle, part of a giant onslaught that will feature multiple body types, and not everyone might want the ID 3 itself over, say, an ID Buzz or an ID Crozz. On the other hand, the Taycan is the first electric Porsche, which carries a bit of cachet, and Porsche fanatics and moneyed EV geeks alike are probably champing at the bit to pick a Taycan up as quickly as possible.Porsche is set to unveil the Taycan in early September. While it’s working on the frontend stuff, it’s also massively investing in its backend, throwing some 6 billion euro at its manufacturing facilities to handle Taycan production. The automaker is clearly impressed with demand for the car, as it’s already made moves to double first-year production from 20,000 cars to 40,000. With a starting price between the Cayenne and Panamera, it shouldn’t break the bank, either.(Hat tip to InsideEVs!) 0 42 Photos Ice drifting in Porsche’s all-electric Taycan 2020 Toyota 4Runner first drive: Same as it ever was — mostly 5:27 Electric Cars Sports Cars Future Cars Hatchbacks More From Roadshow 2020 Mini JCW Clubman first drive: A fast alternative for the crossover-averse Porsche Volkswagen 2020 Kia Soul review: Well-rounded box
A group of Rohingya refugee people walk in the water after crossing the Bangladesh-Myanmar border in Teknaf. Reuters File PhotoSome 647,000 new arrivals of Rohingyas were reported as of 12 December, according to IOM Needs and Population Monitoring (NPM) report released on Wednesday, reports UNB.The increase in the number of refugees is not as a result of a significant influx of refugees across the border, but instead due to strengthened assessments, said the UN Migration Agency.The full report and dataset will be available in the coming days.This report, produced by Inter Sector Coordination Group (ISCG) in collaboration with humanitarian partners, covered the 8-11 December period.
The cabinet on Monday approved in principle the draft of “the Chittagong Hill Tracts (Land Acquisition) Regulation (Amendment) Act, 2019”.It has proposed removal of disparity in compensation for land acquisition in the hills and the plain land.“An ordinance to this end was promulgated at the end of the previous (Awami League) government. . . It will now be turned into a law,” cabinet secretary Mohammad Shafiul Alam told reporters after the maiden meeting of the new cabinet.Alam said earlier 15 per cent compensation was given for acquisition of land in the hills, while the amount was 300 percent in the case of plain land. The ordinance fixed 300 per cent compensation for land acquisition both in hill and plain land areas, he said.He said the cabinet also in principle gave final endorsement to the draft of “The Brick Making and Kiln Setting Up (Control) (Amendment), Act, 2018”.He said the cabinet earlier approved the law and it was promulgated as an ordinance.“The draft law was placed before the cabinet today as there is a legal obligation to submit it to the Jatiya Sangsad,” he said.The cabinet secretary said the cabinet also gave final approval to the draft of “The Jatiya Samajkalyan Parishad Act, 2018”.Jatiya Samajkalyan Parishad, he said, has been running since 1956 through a resolution and it was reconstituted in 1972.“The parishad (council) has been running through a government decision as there was no law to this effect. So a new law has been proposed to run the parishad smoothly,” he said.Under the proposed law, the cabinet secretary said, there will be an 84-member governing body of the council to be headed by the social welfare minister. The council will have to hold at least two meetings in a year, Alam said.The cabinet secretary said the cabinet approved the draft of the national Action Plan on the disabled people in the light of the ‘Persons with Disabilities Rights and Protection Act 2013’ and the ‘Persons with Disabilities Rights and Protection Rules 2015’.He said the law has been proposed to ensure the smooth accessibility of the persons with disabilities to the public transports and establishments like educational institutions, hospitals, bus, launch and rail stations, airports, land ports and river ports, cyclone shelters, cultural function venues, places of worships and flyovers.Replying to a question, Alam said the quota for the disabled people still exists in the government jobs. “The provision still exists there and it is yet to be curtailed,” he said, adding that any law cannot be superseded through an administrative order.Alam said the cabinet approved the draft speech of president Abdul Hamid for the inaugural session of the 11th Parliament, which will start on 30 January.The cabinet secretary said full speech will have some 75,000 words, which will be tabled in the House at the maiden session of the new parliament.But the president will read out the short version of his written speech having 6,000 words in parliament.The speech will focus on the country’s overall scenario including economic development and activities, the government’s measures taken to establish good governance, the activities taken for implementing the Vision 2021 and the Vision 2041, and the government’s measures and successes in improvement of the country’s socioeconomic status, he said.Alam said the cabinet okayed the draft of “The Bangladesh Industrial and Technical Assistance Center Act, 2018.He said at the outset of the meeting, the cabinet adopted an obituary reference at the death of former public administration minister, valiant freedom fighter and ex-Awami League general secretary Syed Ashraful Islam.“Syed Ashraf was a valiant freedom fighter and ideal politician and his death is an irreparable loss to the nation,” the cabinet secretary said, quoting the reference.
Photo via Twitter @liuba4congressThe Justice Department announced this week it is reviewing whether weapons using bump stocks should be considered illegal machine guns under federal lawRepublicans rammed a bill through the House on Wednesday that would make it easier for gun owners to legally carry concealed weapons across state lines, the first significant action on guns in Congress since mass shootings in Nevada and Texas killed more than 80 people.The House approved the bill, 231-198, largely along party lines. Six Democrats voted yes, while 14 Republicans voted no.The measure would allow gun owners with a state-issued concealed-carry permit to carry a handgun in any state that allows concealed weapons. It now goes to the Senate.Houston Police Chief Art Acevedo expressed discontent on his Twitter account about the right to carry concealed weapons across state lines. The degradation of State rights & erosion of state LTC laws/processes isn’t supported by most responsible gun-owners in Texas and beyond. Can’t believe some who claim to champion States’ Rights voted for this. We need national LTC standard similar to TX. https://t.co/ipliLoOxhX— Chief Art Acevedo (@ArtAcevedo) December 7, 2017Acevedo said to The Columbus Dispatch that Texas, despite being a strong gun rights state, has a “very thoughtful” concealed carry process that includes a background check and safety test. Other states don’t necessarily have such requirements, he said. Houston Police Chief Art Acevedo.“We have a process in place that assures law enforcement that they’re dealing with someone who has gone through a background check, is not a criminal and has proven to be a responsible gun owner,” he said.Acevedo said if the bill passes, “it will create, in essence, a nationwide law that would require all states to honor a permit from any state” regardless of the rules.Sen. John Cornyn of Texas, the No. 2 Republican in the Senate, co-sponsored a bipartisan bill bolstering the National Instant Criminal Background Check System, or NICS.While he supports the concealed-carry measure, “I think it’s a mistake to try to combine this with the ‘Fix NICS’ background check,” Cornyn told reporters.The legislation also would order the Justice Department to study bump stocks, including how often they are used in a crime. Share
– / 4The Near Northside neighborhood is home to about 25,000 people and about a third live below the poverty line. The Houston Health Department said the neighborhood just north of downtown struggles with a lot of issues, including the condition of its housing stock. It’s estimated about 92 percent of the homes in the neighborhood are in need of lead paint abatement.The United States banned lead in household paints in the 1970’s but some older homes still have it. And officials say 25 percent of Near Northside children who were tested showed elevated lead levels in their blood.Efforts to improve the neighborhood’s health and safety will now benefit from a new $250,000 grant from the national “BUILD Health Challenge.” The Near Northside project was one of 19 around the country chosen for the grants. Along with the Houston Health Department, the non-profit housing corporation Avenue and the Memorial Hermann Health System are also participating.Avenue Deputy Director Jenifer Wagley said Near Northside is just one of Houston’s old neighborhoods that continues to struggle with ongoing problems.“Even before Harvey it was hard for people to have safe, affordable housing,” said Wagley. “After Harvey the crisis has only intensified.”Wagley explained that one of the things they’re working on in Near Northside is identifying homes that have cracked and peeling lead paint. Neighborhood volunteers have been walking in the blocks to talk to residents about remediation programs that could help.“We are standing in the midst of what I think is an amazing circle right here,” added Wagley. “What does it take to really transform people’s health? How do we improve health outcomes? Should your zip code dictate how long you can live?”The Near Northside effort is also looking at other projects that could improve the neighborhood’s health, like adding more green space for recreation. To embed this piece of audio in your site, please use this code: X 00:00 /00:00 Listen Share
Altice USA Pools Cheddar, i24 News Resources to Expand U.S. Coverage Cheddar Acquired by Cable Operator Altice USA for $200 Million CuriosityStream launched in 2015 as the brainchild of Hendricks, the founder of cable’s Discovery Channel. The service offers an array of documentary and factual programming for $3 a month or $20 a year.John Hendricks, Founder and Chairman of CuriosityStream, commented: “Today, consumers are beginning to view on-demand streaming services that dependably deliver movies, general television entertainment and factual content, such as Netflix, Hulu and CuriosityStream respectively, as standard viewing requirements. It is only natural that forward-leaning distributors such as Altice USA are finding ways to bundle top streaming services into their universal customer offerings.”CuriosityStream content will also be added to Altice’s roster of on-demand programming distributed via its set-top boxes.“With today’s announcement, nearly 5 million more households will be treated to thousands of the world’s best factual programs across all non-fiction genres including science, nature, history, technology, current events, lifestyles, human adventure, and more,” said Clint Stinchcomb, CuriosityStream president and CEO, Related Altice USA has set a deal with John Hendricks’ CuriosityStream to expand distribution of the science- and history-focused subscription streaming service.The deal will make CuriosityStream available to all Altice USA’s 4.9 million customers across 21 states, including a big cluster serving New York and Connecticut. Altice also plans to add the CuriosityStream app to its digital operating system.“We’re always looking at ways to enrich the customer experience, which is why we are pleased to bring CuriosityStream’s rich 4K visuals and storytelling to our Optimum and Suddenlink customers as a value-added benefit,” said Hakim Boubazine, Altice USA co-president and chief operating officer. “Whether through traditional video or digital streaming offerings, our platform enables the delivery of all types of content to our customers so they can access what they want, when they want it.” ×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15 Popular on Variety
The proposed model of cytosolic mobility: (Red box) objects (red spheres) larger than the pore size of the cytoskeleton (50-75 nm) are trapped in a viscoelastic medium and experience restricted diffusion, (green box) if objects are perfectly inert they diffuse freely without hindrance due to obstacles, (purple box) when objects interact with intracellular components diffusion is slowed down but remains Brownian, (yellow box) if interactions increase to the point that immobilization time is longer than the time of observation, the diffusion is significantly slowed down to become anomalous, known as subdiffusion. Credit: Nature Materials (2018) doi: 10.1038/s41563-018-0120-7 Play Representative videos of 25 nm fluorescently labelled NPs diffusing in HeLa cells after pinocytic loading for single-particle tracking experiments. Top panel: unburst vesicles with encapsulated NPs; particles in the intact vesicles move very fast and cannot be tracked individually. Bottom panel: examples of typical regions of interest selected for single-particle tracking analysis of NPs, systematically excluding the unburst vesicles. Behavioral difference of free versus encapsulated NPs ensured a reliable discrimination between the two cases. Images were acquired every 10 ms; video was encoded at 30 frames per second (fps). Scale bar 1 µm. Credit: Nature Materials (2018), doi: 10.1038/s41563-018-0120-7. A brief osmotic shock enabled the dispersion of NPs into the cytoplasm. The NP’s diffusion-based exploration of the cell’s interior was monitored by extensive single-particle tracking experiments. Using this approach, a variety of NP surface modifications and particle sizes ranging from 15 to 75 nm were observed to interact with the surroundings for pronounced diffusion anomalies. , Cell © 2018 Phys.org The experimental data were also explained with a minimal model based on continuous-time random walks, where particles were described to take power-law-distributed rests between periods of free diffusion motion. With this approach, the findings on MSD could be reproduced and captured as particle trajectories. Future work is required to explore if these results also apply to crowds of one to 10 nm-sized macromolecules in cells. Gaining an understanding of how anomalous random walks can be altered when modifying non-equilibrium conditions in cells (such as changed metabolic states) will keep both experimentalists and theorists busy. Overall, the researchers proposed a unified framework to describe the dynamics of diffusion related to nanosized objects in the cell cytoplasm. The study also provided a quantitative benchmarking tool to design perfectly inert NPs that could diffuse within cells unhindered by obstacles, and defined them as “lone maze runners.” Such insights may become crucial to design intracellular drug delivery pathways to easily reach molecular targets within cells in the future. Citation: Maze runners and square dancers: Cytosolic diffusion of nanosized objects in mammalian cells (2018, August 15) retrieved 18 August 2019 from https://phys.org/news/2018-08-maze-runners-square-dancers-cytosolic.html Cells are complex, multi-compartmentalized entities of matter enclosed with a variety of membrane-bound organelles ranging from the microscale (µm) down to the nanoscale (nm) in diameter. These structures intermingle in a crowded aqueous phase known as the cytoplasm, within which diffusion deviates from Brownian motion. Understanding the concept of “cell crowding” and the impact on intracellular mobility can enable controlled diffusion within cells for improved drug delivery and other medical applications. The eukaryotic cytoplasm is a biphasic poroelastic (fluid and solid interaction) medium, containing a fluid phase (cytosol with water and soluble proteins) and a solid phase (cytoskeleton and other organelles). PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen Explore further , Reports on Progress in Physics More information: Fred Etoc et al. Non-specific interactions govern cytosolic diffusion of nanosized objects in mammalian cells, Nature Materials (2018). DOI: 10.1038/s41563-018-0120-7 Matthias Weiss. A tale about square dancers and maze runners, Nature Materials (2018). DOI: 10.1038/s41563-018-0126-1A. Einstein. Über die von der molekularkinetischen Theorie der Wärme geforderte Bewegung von in ruhenden Flüssigkeiten suspendierten Teilchen, Annalen der Physik (2007). DOI: 10.1002/andp.19053220806 Alice B. Fulton. How crowded is the cytoplasm?, Cell (2004). DOI: 10.1016/0092-8674(82)90231-8 Felix Höfling et al. Anomalous transport in the crowded world of biological cells, Reports on Progress in Physics (2013). DOI: 10.1088/0034-4885/76/4/046602 O. Bénichou et al. Geometry-controlled kinetics, Nature Chemistry (2010). DOI: 10.1038/nchem.622 Experiments conducted with tracers on intracellular motion have typically revealed both Brownian and subdiffusive motion (or anomalous diffusion). High concentrations of macromolecules in the cytoplasm described as “obstructive molecular crowding” and biochemical interactions (electrostatic or hydrophobic) naturally affect the mobility of intracellular tracers. As a result, a fundamental question has remained unresolved: Can a unified framework account for the large variability of behaviors observed in cytosolic diffusion? Now writing in Nature Materials, Fred Etoc and colleagues have used single-particle tracking of fluorescent nanoparticle (NP) tracers to observe and propose a unified framework that describes the diffusion dynamics of nanosized objects in the eukaryotic cell cytoplasm.The researchers demonstrate:Inert objects were unaffected by obstructive molecular crowding to show Brownian motion, diffusing in a medium of low viscosity—if they were below approximately 75 nm in size. The researchers metaphorically compared them to “maze runners”Tracers that were approximately 25 nm in size but with increased non-specific interactions slowed down diffusion by three orders of magnitude, to gradually become anomalous and were compared to “square dancers”The strength of non-specific interactions is captured into a single parameter using a simple continuous time random walk (CTRW) model, a textbook model that describes the random walk performed by diffusing particles. By fixing a few basic properties of the random walk, it was possible to observe that diffusing particles explored an area (mean square displacement – MSD) that grew linearly in time. To define the phenomenon of intracellular motion experimentally, Etoc and co-workers hijacked a cellular entry gate known as the pinocytosis pathway (observed with vesicle formation to transport biological materials), to import functionalized and fluorescently labelled nanoparticles (NPs) in to living HeLa cells. Cytoplasmic diffusion of individual NPs (20 to 50 NPs per cell) was recorded by time-lapse microscopy and quantified using single-particle tracking analysis. In the cytoplasm of living HeLa cells non-specific interactions mainly contribute to anomalous diffusion. By changing the surface properties of NPs from strong to almost vanishing interactions within the interior of living cells, the trajectories of interacting NPs (square dancers) were shown to exhibit significant anomalous diffusion (indicated by red regions in density plots). In contrast, non-interacting NPs (lonesome maze runners) underwent normal diffusion. Adapted from doi:10.1038/s41563-018-0120-7. Credit: Nature Materials (2018), doi: 10.1038/s41563-018-0126-1. In the study, Etoc et al. estimated mobility at short timescales by computing time averaged MSD at 60 ms, expressed in terms of the diffusion coefficient D60ms To represent the behavior of the whole population of NPs in each condition, the distribution of the parameters α (anomalous exponent) and D60ms arising from each individual trajectory, was presented as a two-dimensional (2-D) density map. Such density plots for hundreds of trajectories and conditions that integrated the results of α and D60ms were summarized elegantly in the findings. , Nature Chemistry The hidden order in DNA diffusion Journal information: Nature Materials This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Register Now » I never truly experienced the great Portland-Seattle tech migration first hand. Oh, sure, I always heard about it in the background. People couldn’t afford the Bay Area, so periodically various acquaintances might disappear to the rainy north.Skilled American tech workers are leaving the Bay Area faster than they are arriving, so I haven’t been all that surprised. It didn’t really hit home, though, until recent months when a long-time, close coworker and friend, Janine Kahn, who I worked with at Village Voice Media in days gone by, decided to get out of Dodge (or San Francisco in my case). She’d always been one of my best San Francisco media friends, and we shared countless lunches and cupcakes. Time marches on though, and she eventually got an even better position running the digital editorial side of Lumina Media. Even more importantly, she found a good man, who became her husband. This good man found a fancy job in Oregon.“My husband, who also works in tech, got a job as a senior engineer at a dev. agency in Portland, and I work remote, so we decided to give it a shot,” she says. “It doesn’t hurt that we’re renting an entire house for less than our SF one-bedroom now.”Yes, that type of story forms much the core of why there’s a Pacific Northwest tech migration.Google gets in the act.Of course, Google is a part of this major tech trend as well. They recently decided to open offices in Portland too. The move makes Portland one of the latest locations across the globe for the company, including Austin, Los Angeles, Milan, Mexico and Egypt. A local presence gives Google and other companies the ability to better serve customers in each area.This is just a harbinger of things to come. As Portland grows, even more businesses will join Google there. The area has already had a tech worker influx rivaled only by the country’s biggest tech hubs. Here are a few reasons Portland, like Austin, Seattle and others, is capturing the attention of the Silicon Valley worker.Thriving tech industry.Between 2010 and 2013, Portland’s tech talent pool increased by 28 percent, which was a faster rate than Silicon Valley, where the talent pool grew only 20.8 percent. Even Austin, which has long been home to Apple, Google and othe huge tech companies, had slower growth than Portland at 26.5 percent. With so many talented professionals now, Portland has become a popular location for tech giants and startups alike.Hewlett Packard, eBay, Salesforce, New Relic and Airbnb are just a few of the tech companies with offices in Portland. But the city has plenty of its own tech companies, giving it the nickname “Silicon Forest.” The city is the hometown of Tripwire, Digital Trends and Cloudability, as well as numerous other startups and corporations in a variety of industries. This has created a culture of innovation in Northwest Oregon that makes new companies want to locate there.Low cost of living.This is the preeminent reason why workers are looking to leave Silicon Valley. A tech worker can live much more comfortably in Portland than San Francisco or Palo Alto, with much lower housing costs. While tech workers can easily earn six figures in Silicon Valley, tech-sector salaries in Portland are on the rise, up 9 percent between 2013 and 2014. From 2008 to 2014, Portland’s tech salaries increased 18 percent.Like Silicon Valley, the closer you get to Portland’s tech hub, the more expensive the housing is. However, many of the area’s technology workers choose to live in one of the more affordable suburbs of Portland, which also gives families access to great schools. Depending on a worker’s willingness to commute, there are several suburbs that are good places to live. It adds up to something much more attractive than the nasty commute along the various highways throughout the Bay Area.Work-life balance.Work-life balance is often mentioned as a benefit to living in the Portland area. Part of this could be the growing popularity of telecommuting in the city. One study revealed that 7 percent of the city’s workers now work from home and that number is growing. Nationally, 2.6 percent of the workforce telecommutes on a daily basis, making Portland a preferred city for those who want a commute that involves merely walking a few steps to a home office. Studies have shown that working from home allows for a better work-life balance, which is a priority for some of the top up-and-coming technology professionals.Tech workers increasingly seek work-life balance, especially those whose work requires long hours and years of dedication. Portland offers a wide variety of options for tech workers with hobbies, from its big music scene to its museums and art galleries. Many other cities have this, as well, but a shorter work commute and the ability to work from home could help tech workers relieve the pressure they feel in other tech hubs as they try to find a work-life balance that often seems to elude them.Portland is one of many areas seeing rapid growth due to technology companies. With so many professionals choosing the area, it will only continue to attract more organizations looking to capitalize on talent there. The tantalizing lifestyle of the city gives workers a combination of affordability and fun that can’t be found at the center of the tech world. This is good though. A healthy U.S. tech economy can’t be located in one region. It needs to be a part of mutliple regions, so it can drive greater benefit for the national economy as a whole. 5 min read Opinions expressed by Entrepreneur contributors are their own. Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global April 12, 2016 Growing a business sometimes requires thinking outside the box.
Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals 2 min read Opinions expressed by Entrepreneur contributors are their own. Entrepreneur has affiliate partnership with TechBargains so we may get a share of the revenue from your purchase.Thanks to our friends at TechBargains, we’ve rounded up three can’t-miss deals on stuff you won’t want to miss. Check it out:1. Dell XPS 8900 i7 Quad-Core Desktop for only $699This is the lowest price we’ve seen on the desktop (save $300 off list price) and it’s a favorite home office workstation.2. Amazon Deal of the Day: 25 Percent off Select Kindle & Fire Accessories If you bought a Kindle or Fire tablet during Prime Day, now is a great time to get travel accessories such as custom fit covers, screen protectors and sleeves for your new device.3. Blu R1 8GB Unlocked Smartphone for $49.99 (for Prime Users)Never heard of a Blu smartphone? Blu is a fast-growing mobile phone manufacturer. Prime members can get these Blu R1 Unlocked smartphones at $50 off. These are dual SIM phones with a 5″ 720p screen, which is fantastic if you need an inexpensive phone to travel with or if you simply need a backup phone. We recommend the 16GB version for only $10 more as it has 1GB more RAM.Disclosure: This is brought to you by the Entrepreneur Partner Studio. Our goal is to feature products and services that we think you’ll find interesting and useful. If you purchase them, we may get a small share of the revenue from the sale from our commerce partners. July 20, 2016 Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. Register Now »