The spring edition of the Boston Calling Festival is set to take place at the Massachusetts’ Harvard Athletic Complex on May 25-27. The lineup features headlining slots from Eminem, The Killers, and Jack White, marking his first scheduled live performance with his new band in 2018. Queens of the Stone Age, The National, Paramore, Tyler, The Creator, Khalid, Bryson Tiller, Portugal. The Man, Fleet Foxes, St. Vincent, The Decemberists, Brockhampton, Maggie Rogers, and Royal Blood round out the top three lines of the diverse lineup. Also performing are Manchester Orchestra, Dirty Projectors, Pussy Riot, Thundercat, TAUK, and many more.Early Bird tickets are currently available here. For more information, head to the festival website.
Following a tissue graft transplant — such as that of the face, hand, arm, or leg — it is standard for doctors to give transplant recipients immunosuppressant drugs immediately to prevent their immune systems from rejecting and attacking the new body part. However, that incurs the risk of toxicities and side effects, because suppressing the immune system can make a patient vulnerable to infection.In a global collaboration, researchers from Harvard-affiliated Brigham and Women’s Hospital (BWH), the Institute for Stem Cell Biology and Regenerative Medicine in Bangalore, India, and University Hospital of Bern, Switzerland, have developed a way to deliver immunosuppressant drugs locally and when prompted, through the use of a biomaterial that self-assembles into a hydrogel, a gelatinlike material. The novel system is able to targeted and controlled release of the medication, so that it is delivered where and when it is needed.The study was published online today in Science Translational Medicine.The hydrogel-drug combo, which contains the immunosuppressant drug tacrolimus, is injected under the skin after transplant surgery. The hydrogel remains inactive until it detects an inflammation/immune response from the transplant site, at which point it delivers the immunosuppressant drug within the transplanted graft for months.In pre-clinical studies conducted by the researchers, a one-time, local injection of the hydrogel-drug combo prevented graft rejection for more than 100 days. This compared with 35.5 days for recipients receiving only tacrolimus, and 11 days for recipients without treatment or only receiving hydrogel.The innovation may also be applied in medical situations outside of transplant surgery.“This new approach to delivering immunosuppressant therapy suggests that local delivery of the drug to the grafted tissue has benefits in reducing toxicity, as well as markedly improving therapeutic outcomes, and may lead to a paradigm shift in clinical immunosuppressive therapy in transplant surgery,” said Harvard Medical School associate professor of medicine Jeff Karp, Division of Biomedical Engineering, BWH Department of Medicine, co-corresponding study author.Inflammation-directed drug release offers judicious use of a locally injected drug that extends the release for months while eliminating systemic toxicity, added Robert Rieben, associate professor of transplantation immunology, Department of Clinical Research, University of Bern, co-corresponding study author. “Continuous release of the drugs irrespective of disease severity is a hallmark of existing drug delivery vehicles and could be a thing of the past.”“This safe, controlled release platform approach functions for over three months from a single injection, and that has broad implications,” said Karp. “Nearly every disease has an inflammatory component. Thus we believe the materials we have developed could be used for localized treatment of multiple inflammatory diseases.”Added Praveen Kumar Vemula, co-corresponding study author: “This approach should also improve patient compliance, as it obviates the need for daily medications. Also, we plan to expand this prototype for the treatment of numerous diseases such as psoriasis, arthritis, and cancer.” Vemula, now affiliated with the Institute for Stem Cell Biology and Regenerative Medicine in Bangalore, India, developed the hydrogel with Karp while a postdoc in the Karp laboratory.This research was supported by the National Institutes of Health, American Society for Surgery of the Hand, Olga Mayenfisch Foundation, Julia Bangerter-Rhyner Foundation, and a Harvard Institute of Translational Immunology/Helmsley Trust Pilot Grant.Karp is a founder of, and has a financial interest in, Skintifique, a company that is developing self-assembled hydrogels for skin applications. The Karp lab developed the hydrogel technology and it was licensed by BWH to Skintifique.
Read Full Story A groundbreaking new report on women and health has found that women are contributing roughly $3 trillion to global health care, but that nearly half of this work—2.35% of global GDP—is unpaid and unrecognized.The June 5, 2015 Lancet report, issued by the Commission on Women and Health, is being launched the same day at a symposium at Harvard T.H. Chan School of Public Health. The report offers one of the most exhaustive analyses to date of the evidence surrounding the complex relationships between women and health, and demonstrates that women’s distinctive contribution to society is under-recognized and undervalued—economically, socially, politically, and culturally. It examines women’s health needs as well as their critical roles as members of the health workforce and caregivers in their families and communities, and makes recommendations to advance the women and health agenda.The Commission on Women and Health, co-chaired by Ana Langer, professor of the practice of public health and director of the Women and Health Initiative and Maternal Health Task Force at Harvard Chan School, is a partnership between The Lancet, the Women and Health Initiative, and the University of Pennsylvania School of Nursing. Other Harvard-affiliated faculty who served as commissioners and authors on the report included Dean Julio Frenk and Professor of Global Health Systems Rifat Atun, both from Harvard Chan School, and Felicia Knaul, associate professor at Harvard Medical School.
Burlington, VT December 8, 2006 Northfield Savings Bank has become the new Presenting Sponsor of the Burlington Discover Jazz Festival, Burlingtons annual 10-day community celebration. In keeping with its commitment to community, Northfield Savings Bank is helping to ensure that the Festival, a 24-year Vermont tradition, continues to enthrall Vermonters and visitors alike and serves to energize the city and local businesses. Northfield Savings Bank is proud to be able to step up our support of Vermonts largest multi-cultural event, and help continue the tradition of animating every corner of downtown Burlington with excitement offering unforgettable experiences for the entire community, said Tina de la Torre, Director of Marketing and Community Relations for Northfield Savings Bank. The changing of the guard marks a new day for the Festival, as its Founding and longtime Presenting Sponsor, the Pepsi Cola Bottling Company of Burlington, modifies its role in the celebration it helped create and nurture. Northfield Savings Bank first became involved with the festival in 2004.We are so grateful to Pepsi for making this Festival what it is today and we look forward to Northfield Savings Bank setting the stage for its bright future, said Andrea Rogers, Executive Director of the Festival-producing Flynn Center for the Performing Arts. The Burlington Discover Jazz Festival started 24 years ago to give Vermont’s flourishing jazz community the recognition it deserved a celebration combining incredible Vermont talent with jazz legends from every corner of the globe. Produced by the Flynn Center for the Performing Arts, in association with Burlington City Arts, the Festival has grown throughout the years, but its mission to provide enjoyment and education through discovery of jazz in all its forms has remained constant. This years Festival will be held June 1-10, 2007 in performance spaces, parks, and outdoor venues all over town. The line-up will be announced and tickets will go on sale in mid-April, 2007. # # # About Northfield Savings BankNorthfield Savings Bank is an independent mutual organization owned by its depositors, and has been an active part of Vermont communities for nearly 140 years. An annual dividend equal to 10% or more of profits, otherwise paid to stockholders in a public company, is invested in local communities through contributions to Vermont non-profit organizations. NSB has assets of $516 million, employs approximately 145 people, and operates 13 branches throughout Central Vermont and Chittenden County. Web: www.discoverjazz.com(link is external)
Although you are not in a supervisory role within your organization, that doesn’t mean you can’t be a leader to those at the office. Even if no one directly reports to you, you can still lead by example without being “bossy.” True leaders aren’t necessarily in that position because of their job title, but instead they possess a specific skill set that others look up to. Below are a few ways you can be a leader at work even though you’re not the boss.Spread the loveUnfortunately, many bosses don’t take the time to compliment or give credit to their team. This is where you can step in to spread some love. If you notice a colleague is excelling in a certain aspect of their job, give them the props they deserve. Getting a good pat on the back from a coworker can be just as encouraging as a kind word from a boss.Communicate carefullyLeaders don’t complain when things don’t go their way. Instead, they are open and honest with others about their thoughts and concerns. Even if you are not the boss, you can still lead by communicating effectively with your colleagues. Don’t be afraid to ask questions if you are unsure of how to move forward. Lean on those around you to develop a strong sense of teamwork and collaboration.Lend a handJust because others aren’t reporting to you doesn’t mean you can’t help them when they are struggling. Even if they don’t accept your offer to help out, just extending a helping hand will show them you care about their work performance. Don’t be afraid to go out of your way for teammates because that demonstrates a humility that only true leaders possess. Hopefully if you are there when someone at work needs you, they will help you out down the road if you hit a rough patch.Take a riskReal leaders get to where they are because of the risks they’ve taken throughout their career. Others recognize when a leader steps outside the box and even if you’re not the boss, you can still move out of your comfort zone. Impress your colleagues with your creativity and innovative outlook. As a result, they will more often than not be inspired and follow suit. 260SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblr,Wendy Moody Wendy Moody is a Senior Editor with CUInsight.com. Wendy works with the editorial team to help edit the content including current news, press releases, jobs and events. She keeps … Web: www.cuinsight.com Details
Cases of a mutated strain of Covid-19 have been detected that may undermine future vaccines.- Advertisement –
Jodi Lavoie-Carnes, 48, a dental hygienist who lives in Dover, N.H., supported President Trump for re-election. On Saturday, she was shocked and disturbed by the boisterous celebrations of Biden supporters, who had gathered in her town waving profane anti-Trump signs.The tone was so negative that she wondered what lies ahead for the country.- Advertisement – Mr. Thompson pointed to “computer glitches and all these new ballots” as potential sources of fraudulent votes. “I want my guy to win,” he said. “But if he loses fair and squarely, I’m in. But that doesn’t seem to be the case on the other side.”In Washington, a few dozen Trump supporters gathered outside the Capitol shortly after 1 p.m. in a peaceful protest against the election results. One person waved a sign reading “four more years,” while another waved a sign stating “Stop the Steal.” Larry Thompson, who had voted for President Trump in Prosper, Texas, initially believed that Mr. Trump would win re-election in a landslide. Even after media outlets had called the race for Mr. Biden, Mr. Thompson, 75, still thought the president would ultimately prevail.“I don’t believe what The A.P. has called here for Biden, especially because of all the discrepancies that are out there,” Mr. Thompson said. “I’m not agreeing with that assessment.”- Advertisement – Around the country, Trump supporters greeted news that Joseph R. Biden Jr. had won the election with a combination of disappointment and disbelief. – Advertisement – “I’m like, are you serious?” said Ms. Lavoie-Carnes, who ran unsuccessfully as a Republican for the New Hampshire State House this year. “The language doesn’t need to be there. My children need to drive by that.”She said it was President-elect Joseph R. Biden Jr.’s responsibility to keep the tone of celebrations civil.“Now you’re an elect, so calm them down,” she said.- Advertisement –
Feb 24, 2006 (CIDRAP News) – Authorities in the former Soviet republic of Georgia today reported finding H5N1 avian influenza in swans, making Georgia the 16th country to report its first case this month.Dead swans found in the village of Adliya, in the Black Sea coastal region of Adjara, tested positive, said Prime Minister Zurab Nogaideli, as quoted in an Agence France-Presse (AFP) report.A laboratory in the Georgian capital of Tbilisi identified H5N1 in the birds, Nogaideli said. He said samples have been sent to London for further testing.Georgia lies on the east side of the Black Sea and borders Turkey and Azerbaijan, which have both been hit by avian flu in recent months. Turkey has had both poultry outbreaks and human cases; Azerbaijan has found the virus in wild birds.Countries that have reported their first H5N1 cases in birds this month, according to the World Health Organization (WHO) and recent news reports, include Iraq, Nigeria, Azerbaijan, Bulgaria, Greece, Italy, Slovenia, Iran, Austria, Germany, Egypt, India, France, Hungary, and Slovakia.In other developments today, France reported finding an H5 virus on a turkey farm, while the WHO said it has uncovered no evidence of human avian flu transmission between two relatives in Iraq. In addition, South Korea said four people who helped slaughter poultry during an avian flu outbreak 2 years ago have tested positive for past infection with the virus, though they were never sick.In France, an agriculture official said turkeys on a farm in the southeastern region of Ain were infected with an H5 virus, but further tests were needed to determine if it was H5N1, according to an AFP report. If so, it will mark the first known outbreak on a farm in France. The farm is in the same area where the virus was recently found in two wild ducks.A WHO team that recently visited Iraq to assess the avian flu situation there determined that the two Iraqis who recently died of the disease did not pass the virus between them, according to Dr. Naeema Al Gasseer, the WHO representative in Iraq.”There is no human-to-human case in Iraq,” Al Gasseer said during a teleconference from WHO headquarters in Geneva today. She was part of a team that looked into the cases of 15-year-old girl who died Jan 17 and her 39-year-old uncle, who died Jan 27.Both victims, who were close neighbors in the northern province of Sulaimaniyah, had slaughtered, defeathered, and cooked poultry before their illnesses, Al Gasseer said.She said another suspected human case, in Amara in southern Iraq, has been ruled out, but one suspected case is still under investigation in the province of Diyala, which is northeast of Baghdad. Iraq also has outbreaks of an H5 virus in poultry in one district of Sulaimaniyah and one in Diyala, she reported.Al Gasseer said the Iraqi government has generally responded well to the avian flu outbreaks and human cases, with high-level officials showing openness and a strong commitment to dealing with the problem.However, she said there was “tension” over the WHO’s insistence that suspected cases be confirmed by testing at WHO reference labs before announcements are made. “There was a misconception at all levels that specimens should be tested only in Iraq,” she said.The WHO team saw the results of widespread poultry culling in Sulaimaniyah, Al Gasseer said. In driving through the region, “We barely could see villages with backyard chickens. So this was a very big change of behavior that we observed.”She noted that the WHO is concerned that families receive some compensation for their lost poultry. The agency has proposed that the Iraqi government consult with the Turkish government, which did widespread culling in recent weeks, on how to provide compensation, she said.The four South Koreans, whose test results were received in their country yesterday according to an AFP report, had assisted in the culling of 5.3 million poultry in late 2003 and early 2004.About 2,000 samples were collected at that time from the workers, but testing was delayed because of a shortage of facilities, said Oh Dae-Kyu, head of the health ministry’s Center for Disease Control and Prevention. Of about 380 samples that were tested, 11 were suspect and so were sent to the United States. Among these were samples from the four people just reported as positive.The remaining samples can now be processed, Dae-Kyo said, because of improved testing capacity. The people are not considered patients in official WHO counts, the AFP story says, because they had no disease symptoms. South Korea declared itself free of avian flu in December 2005.
The Vinkovci Autumn event has been successfully preserving and nurturing Croatian traditional culture and heritage for 52 years, and this year from September 08 to 17 they will bring a series of newspapers that will enrich this prestigious and well-known folklore, tourist, economic and cultural event and attract more. of 150 thousand visitors.Although the main and more attractive events are on Friday, Saturday and Sunday, September 15, 16 and 17, introductory events begin on September 8 when the Fair of Economy, Traditional Crafts and Handicrafts opens and will last all days of Vinkovci Autumns where entrepreneurs and craftsmen at 36 stalls, ten small and ten large houses show a part of what they produce – from traditional products, wicker baskets, pins, shocking caps to handicrafts, fragrant soaps. Caterers, honey producers, producers of dried meat delicacies, brandy and wine, beekeeping equipment, wooden toys and other craftsmen will present themselves.”I would like to thank the media for their support and for showing the Vinkovci Autumns, which have no competition among the events on the continent, as they are. Vinkovci and the whole of Croatia live for this 52nd Vinkovci Autumn from September 8 to 17, when about 10 thousand people participate in them and when our city will be visited by 100 to 150 thousand visitors. I invite guests to visit our city during the 52nd Vinkovci Autumns and spend 10 beautiful days with us”Pointed out Vinkovci Mayor Ivan Bosančić, President of the Organizing Committee of the 52nd Vinkovci Autumns.In the evening, folklore evenings of Vukovar-Srijem County will open, where about 60 KUDs will participate, and the best will represent the county at the state festival of original Croatian folklore. For 47 years, as part of the Vinkovci Autumns, Children’s Autumns have been held, where this year about 60 groups of children with 2500 performers will perform at the inter-county festival of children’s folklore groups and a ceremonial parade. “The grand opening is on Friday, September 8, under the motto “Ex Slavonia” according to the script of our permanent screenwriter Ana Cvenić, where there will be over 200 performers. The inter-county festival of children’s folklore groups and a ceremonial parade is on Saturday and Sunday, September 9 and 10, and on Saturday and Sunday is the State Festival of Original Croatian Folklore, where the 40 best folklore groups will be presented. The most attractive event and the highlight of Autumn is the Sunday parade in which there will be 81 KUDs, and 30 ceremoniously decorated horse-drawn carriages and riders. I think that the program is rich and that visitors and guests of our city will have something to seeand ”said Đurković, secretary of OO and ZAKUD.Mirjam Jukić, director of Promo Cibalae doo, thanked the journalists for their interest in this event, adding that a huge number of journalists applied for accreditations. “Slavonski sokak is a novelty from the 50th edition of the event, and this is the Wine City organized by the company Vinart from Zagreb. The best domestic and foreign winemakers will present themselves in the City, and our intention is to promote the culture of wine drinking with Slavonian kulen and brandy. On our Sokak, the novelty is the stage that was set at the entrance of Sokak this year, and in that part we have prepared a rich program for all ten days.Said Jukic.The liveliest will be in Slavonski sokak, on the plateau in front of the Slavonija Hotel, where there will be a tamburitza or entertainment concert every day next to the Fair, and folklorists and stars of Croatian pop music will take turns in the Vinkovci Autumns tent. Also, for the first time, the ‘Wine City’ is held, in which Croatian and foreign winemakers are presented.On Friday, September 15, the opening ceremony of the 52nd Vinkovci Autumns will be held this year under the name “From Slavonia”, while on Sunday there will be a ceremonial parade of the 52nd Vinkovci Autumns in which 80 KUDs will parade through the streets and squares of Vinkovci. 50 horsemen and 25 ceremoniously decorated horse-drawn carriages, a total of more than 8000 participants.You know how the song goes: Come to Vinkovci.See more about the program and all activities at www.vinkovackejeseni.hr
Topics : Furthermore, the city’s latest COVID-19 daily reproduction number (Rt) stood at 1, said Jakarta Governor Anies Baswedan.An outbreak is considered under control if the number is below 1.“Considering the latest developments, we decided to extend the transitional PSBB until Aug. 13,” Anies said in a virtual press briefing on Thursday.He further appealed to the public, especially businesses and workplaces, to comply with health protocols during the period, which is described as a “transitional” phase with the gradual reopening of several essential services. Jakarta has extended its transitional period from large-scale social restrictions (PSBB) for another two weeks starting on Friday after failing to slow down the daily increase in COVID-19 cases.The capital positivity rate — or the percentage of positive results from all tests — hit 6.5 percent in the past week, above the figure recommended by the World Health Organization (WHO) for relaxations, which is 5 percent or below.Jakarta’s weekly positivity rate was consistently below 5 percent in June and part of July. Anies emphasized that office buildings — many of which had started allowing their employees to come to work — had recorded an alarming rate of new COVID-19 clusters over the past two weeks.“I once again remind everyone that any business is allowed [to open] only in half-capacity while adhering to health protocols and implement alternating working hours,” he said, “If necessary, please allocate five to 10 minutes in the morning to remind all workers about the health protocols.”The city administration will impose progressive fines on businesses repeatedly caught violating PSBB regulations, Anies warned.Jakarta’s first transitional PSBB phase started on June 5 and was initially set to last until July 2. However, the administration extended the phase to July 16 and due to the increasing number of COVID-19 cases, extended it again to July 30.On Thursday, the capital city recorded 397 new confirmed COVID-19 cases, bringing the total number of infections in Jakarta to 20,696, according to the central government’s official tally. Jakarta authorities have done 36,591 swab tests per one million population in the city of 10 million people. (aly)