TCI NATIONAL SECURITY COUNCIL MEETING Recommended for you TCI REPRESENTED BY EIGHT ATHLETES AT NACAC GAMES IN TRINIDAD MINISTRY OF EDUCATION ANNOUNCES 2017 INTERNATIONAL SCHOLARSHIP AWARDEES Facebook Twitter Google+LinkedInPinterestWhatsAppThe Bahamas Department of Labour will launch an upgrade to its local Skills Bank portal, PCRecruiter, on July 21, 2017 to enhance employee placement services. The recruiting and staffing software was first introduced in 2006. However an update and re-launch of this integral tool in the department’s recruitment process is underway.The upgrade is a component of the Ministry of National Security’s “Citizen Security and Justice” Initiative facilitated by a loan from the Inter-American Development Bank (IDB).With levels of unemployment being a matter of national concern, the Department continues to respond to the needs of those job seekers and employers alike through this online data portal that populates data and accordingly matches candidates for suitable available job opportunities.Mrs. Patrenda D. Russell-Brice, Deputy Director of Labour describes this upgrade as “exciting times at the Department.” She emphasized her continued passion for seeing Bahamian job seekers benefit from the opportunity to be employed in roles they qualify for and desire. She stated, “it’s been a long time coming and I am pleased about the upcoming training and launch of the upgraded PCRecruiter system. It is a successful tool for job seekers as well as employers who seek to fill vacancies with suitable Bahamians.”The effectiveness of the system hinges on registration of job seekers as well as registration of employers with job opportunities they wish to fill. The inventory of available jobs will be easily accessible once employers enter their job vacancies in the skills bank.For employers already enrolled – the process requires their signing in and editing their registration information.For employers across The Bahamas who have not yet registered, they are all encouraged to do so by logging intoskillsbank.bahamas.gov.bs where they can create or edit job vacancies, view interviews from job seekers, or browse the database of job seekers.Job seekers must also register in the online skills bank; thereafter they will be able to view job vacancies, post resumes, enquire about jobs, and update their accounts and resumes periodically. Employed individuals wishing to explore options are encouraged to register their skills and qualifications into the skills database system. Similarly, students or citizens residing abroad who are desirous of returning home and wish to secure employment options in advance are encouraged to register.Director of Labour, Mr. A. Robert Farquharson shared that high schools and other local institutions of higher education such as the University of The Bahamas can look forward to teams from the department’s Public Employment Services Unit scheduling tours and visits to their campuses in order to encourage students preparing to enter the work force to register with the skills bank.Individuals who prefer to come in person to register for the PCRecruiter database may visit any Department of Labour sub-office in New Providence or the Family Islands. New Providence locations include Rosetta Street, Robinson Road and Carmichael Road. Family Island locations include Grand Bahama, Eleuthera, Abaco, Exuma, Andros and Bimini.There are no fees associated with the service.For more information on The Bahamas Department of Labour, visit http://www.bahamas.gov.bs/labourThe Bahamas’ Department of Labour is a division of the Ministry of Labour and has responsibility for fostering good industrial relations between employees and employers, while promoting a high level of employment, productivity, human rights and the Decent Work Agenda in accordance with international standards for all citizens and residents of The Commonwealth of The Bahamas.Units within the Department include Industrial Relations (Conciliations), Public Employment Services (Employment Exchange) and the Inspectorate (Occupational Health and Safety).The Bahamas Department of Labour, located on Rosetta Street, facilitates Employment Assistance Services, Employee Placement Services, Formation and Registration of Trade Unions, Reports of Trade Disputes, Registration for Employment, Maritime, Registration of Industrial Agreements and Occupational Health and Safety.There are also two New Providence sub-offices located on Robinson Road and Carmichael Road. Family Island locations include Grand Bahama, Eleuthera, Abaco, Exuma, Andros and Bimini.#MagneticMediaNews#PressRelease Facebook Twitter Google+LinkedInPinterestWhatsApp Related Items:#magneticmedianews, #MinistryOfLabour, #PressRelease
Kylian Mbappe believes he has already become a leader at Paris Saint-Germain after his impressive second-half cameo inspired them to a 2-0 win over MarseillePSG manager Thomas Tuchel benched Mbappe along with Adrien Rabiot from Sunday’s Le Classique for disciplinary reasons after arriving late for the pre-game team talk.However, with the scoreline goalless, Tuchel substituted Eric Maxim Choupo-Moting for Mbappe in the 62nd-minute and the youngster responded emphatically.It took just three minutes for Mbappe to score the opener for PSG before he later assisted Julian Draxler’s injury-time goal to seal a 2-0 win.Now the 19-year-old admits he feels like a leader for a team that wants to down in history.“The team needed this win,” Mbappe told Canal+.Opinion: Neymar will earn respect back from the PSG fans Tomás Pavel Ibarra Meda – September 14, 2019 After completing his incredible return to Parc des Princes, we predict that Neymar will earn the respect back from PSG supporters.The situation between Neymar…“A great team relies on its leaders and they have to make a difference at key moments. I think I can take on that role and I did.“We have to continue on the right path. Marseille showed they have a team that plays with the ball. They had several sequences of play where we were in trouble, so all credit to them.“But we were able to be effective and we leave with the win. We are competitors. We want to go down in history. We mustn’t disregard any match.”Mbappe has now scored 12 goals and added four assists in 10 appearances across all competitions this season.PSG have also now won all eleven of their opening Ligue 1 fixtures this term, which hasn’t been accomplished in any of Europe’s top five leagues since Tottenham in 1960.
(Phys.org) — Research published in the peer-review Journal of the Royal Society Interface on Wednesday presents a close look at the structure and physical properties of silkworm cocoons. The paper’s research efforts could move scientists closer toward coming up with tomorrow’s design principles for materials inspired by silkworm cocoons. Those materials might provide important advancements in materials for such areas as defense and manufacturing. The authors, Fujia Chen, David Porter, and Fritz Vollrath, note that silkworm cocoons have an impressive range of optimal structures. These are lightweight, strong and porous, and ideal for the development of “bio-inspired” composite materials. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Source: Wikimedia Commons The authors examine cocoon structure. Specifically, they present observations and measurements on twenty-five diverse types of cocoons. They set out to correlate their physical properties with the cocoons’ structure and morphology.Some advanced materials that could benefit from that understanding might end up in the manufacture of car panels, helmets and protective suits for mine workers. The study’s research was funded by a grant from the U.S. Air Force.Their work is certainly not the first nor the last that will talk about nature’s silk producers and what scientists can learn. Spider silk is recognized as an intriguing material in that it is strong and tough and elastic enough to stretch several times its original length. Earlier this year, Discover issued a report on lab work at the University of Wyoming, where silk-spinning silkworms were genetically engineered to spin a hybrid material, partly their own silk and partly that of a spider. Also earlier this year, scientists from Germany’s Max Planck Institute for Heart and Lung Research created artificial heart tissue from silk produced by silkworms.Earlier this week, The Engineer reported that scientists from Tufts University in the U.S. bonded silk protein microfibers from silkworm cocoons to a silk protein scaffold to create a material that mimics the stiffness and surface roughness of bone.As for the publication on Wednesday, Prof. David Porter for the last few years has been collaborating with spider expert Fritz Vollrath at Oxford to study polymer science models and spider silk.They are part of The Oxford Silk Group, in the Department of Zoology, at Oxford. In studying the biology of spider silks, they hope to unravel the chemistry and evolution of these materials, along with a focus on spider-web engineering and behavior. As produced by spiders and insects, natural silks are made under benign conditions— ambient temperature, low pressure, and with water as solvent. “Clearly,” according to a statement from the Oxford Silk Group, “this is something we should aim to copy when designing and making fibers for the future.” Silkworms spinning spider webs © 2012 Phys.Org Journal information: Journal of the Royal Society Interface Citation: Silkworm structures drive push for new materials (2012, May 3) retrieved 18 August 2019 from https://phys.org/news/2012-05-silkworm-materials.html Explore further
The proposed model of cytosolic mobility: (Red box) objects (red spheres) larger than the pore size of the cytoskeleton (50-75 nm) are trapped in a viscoelastic medium and experience restricted diffusion, (green box) if objects are perfectly inert they diffuse freely without hindrance due to obstacles, (purple box) when objects interact with intracellular components diffusion is slowed down but remains Brownian, (yellow box) if interactions increase to the point that immobilization time is longer than the time of observation, the diffusion is significantly slowed down to become anomalous, known as subdiffusion. Credit: Nature Materials (2018) doi: 10.1038/s41563-018-0120-7 Play Representative videos of 25 nm fluorescently labelled NPs diffusing in HeLa cells after pinocytic loading for single-particle tracking experiments. Top panel: unburst vesicles with encapsulated NPs; particles in the intact vesicles move very fast and cannot be tracked individually. Bottom panel: examples of typical regions of interest selected for single-particle tracking analysis of NPs, systematically excluding the unburst vesicles. Behavioral difference of free versus encapsulated NPs ensured a reliable discrimination between the two cases. Images were acquired every 10 ms; video was encoded at 30 frames per second (fps). Scale bar 1 µm. Credit: Nature Materials (2018), doi: 10.1038/s41563-018-0120-7. A brief osmotic shock enabled the dispersion of NPs into the cytoplasm. The NP’s diffusion-based exploration of the cell’s interior was monitored by extensive single-particle tracking experiments. Using this approach, a variety of NP surface modifications and particle sizes ranging from 15 to 75 nm were observed to interact with the surroundings for pronounced diffusion anomalies. , Cell © 2018 Phys.org The experimental data were also explained with a minimal model based on continuous-time random walks, where particles were described to take power-law-distributed rests between periods of free diffusion motion. With this approach, the findings on MSD could be reproduced and captured as particle trajectories. Future work is required to explore if these results also apply to crowds of one to 10 nm-sized macromolecules in cells. Gaining an understanding of how anomalous random walks can be altered when modifying non-equilibrium conditions in cells (such as changed metabolic states) will keep both experimentalists and theorists busy. Overall, the researchers proposed a unified framework to describe the dynamics of diffusion related to nanosized objects in the cell cytoplasm. The study also provided a quantitative benchmarking tool to design perfectly inert NPs that could diffuse within cells unhindered by obstacles, and defined them as “lone maze runners.” Such insights may become crucial to design intracellular drug delivery pathways to easily reach molecular targets within cells in the future. Citation: Maze runners and square dancers: Cytosolic diffusion of nanosized objects in mammalian cells (2018, August 15) retrieved 18 August 2019 from https://phys.org/news/2018-08-maze-runners-square-dancers-cytosolic.html Cells are complex, multi-compartmentalized entities of matter enclosed with a variety of membrane-bound organelles ranging from the microscale (µm) down to the nanoscale (nm) in diameter. These structures intermingle in a crowded aqueous phase known as the cytoplasm, within which diffusion deviates from Brownian motion. Understanding the concept of “cell crowding” and the impact on intracellular mobility can enable controlled diffusion within cells for improved drug delivery and other medical applications. The eukaryotic cytoplasm is a biphasic poroelastic (fluid and solid interaction) medium, containing a fluid phase (cytosol with water and soluble proteins) and a solid phase (cytoskeleton and other organelles). PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen Explore further , Reports on Progress in Physics More information: Fred Etoc et al. Non-specific interactions govern cytosolic diffusion of nanosized objects in mammalian cells, Nature Materials (2018). DOI: 10.1038/s41563-018-0120-7 Matthias Weiss. A tale about square dancers and maze runners, Nature Materials (2018). DOI: 10.1038/s41563-018-0126-1A. Einstein. Über die von der molekularkinetischen Theorie der Wärme geforderte Bewegung von in ruhenden Flüssigkeiten suspendierten Teilchen, Annalen der Physik (2007). DOI: 10.1002/andp.19053220806 Alice B. Fulton. How crowded is the cytoplasm?, Cell (2004). DOI: 10.1016/0092-8674(82)90231-8 Felix Höfling et al. Anomalous transport in the crowded world of biological cells, Reports on Progress in Physics (2013). DOI: 10.1088/0034-4885/76/4/046602 O. Bénichou et al. Geometry-controlled kinetics, Nature Chemistry (2010). DOI: 10.1038/nchem.622 Experiments conducted with tracers on intracellular motion have typically revealed both Brownian and subdiffusive motion (or anomalous diffusion). High concentrations of macromolecules in the cytoplasm described as “obstructive molecular crowding” and biochemical interactions (electrostatic or hydrophobic) naturally affect the mobility of intracellular tracers. As a result, a fundamental question has remained unresolved: Can a unified framework account for the large variability of behaviors observed in cytosolic diffusion? Now writing in Nature Materials, Fred Etoc and colleagues have used single-particle tracking of fluorescent nanoparticle (NP) tracers to observe and propose a unified framework that describes the diffusion dynamics of nanosized objects in the eukaryotic cell cytoplasm.The researchers demonstrate:Inert objects were unaffected by obstructive molecular crowding to show Brownian motion, diffusing in a medium of low viscosity—if they were below approximately 75 nm in size. The researchers metaphorically compared them to “maze runners”Tracers that were approximately 25 nm in size but with increased non-specific interactions slowed down diffusion by three orders of magnitude, to gradually become anomalous and were compared to “square dancers”The strength of non-specific interactions is captured into a single parameter using a simple continuous time random walk (CTRW) model, a textbook model that describes the random walk performed by diffusing particles. By fixing a few basic properties of the random walk, it was possible to observe that diffusing particles explored an area (mean square displacement – MSD) that grew linearly in time. To define the phenomenon of intracellular motion experimentally, Etoc and co-workers hijacked a cellular entry gate known as the pinocytosis pathway (observed with vesicle formation to transport biological materials), to import functionalized and fluorescently labelled nanoparticles (NPs) in to living HeLa cells. Cytoplasmic diffusion of individual NPs (20 to 50 NPs per cell) was recorded by time-lapse microscopy and quantified using single-particle tracking analysis. In the cytoplasm of living HeLa cells non-specific interactions mainly contribute to anomalous diffusion. By changing the surface properties of NPs from strong to almost vanishing interactions within the interior of living cells, the trajectories of interacting NPs (square dancers) were shown to exhibit significant anomalous diffusion (indicated by red regions in density plots). In contrast, non-interacting NPs (lonesome maze runners) underwent normal diffusion. Adapted from doi:10.1038/s41563-018-0120-7. Credit: Nature Materials (2018), doi: 10.1038/s41563-018-0126-1. In the study, Etoc et al. estimated mobility at short timescales by computing time averaged MSD at 60 ms, expressed in terms of the diffusion coefficient D60ms To represent the behavior of the whole population of NPs in each condition, the distribution of the parameters α (anomalous exponent) and D60ms arising from each individual trajectory, was presented as a two-dimensional (2-D) density map. Such density plots for hundreds of trajectories and conditions that integrated the results of α and D60ms were summarized elegantly in the findings. , Nature Chemistry The hidden order in DNA diffusion Journal information: Nature Materials This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.